Synthesis of Some Modified Five and Six-membered Heterocyclic Rings with Expected Biological Activity

Eman Ramadan El-Sayed Kasem;

Abstract


u,P-Unsaturated ketones (chalcones or benzalacetophenones) represent active intermediates for the preparation of several heterocyclic ring systems.
Condensation of acetophenone (54) with the appropriate aromatic aldehydes 55a-f in presence of 10% aqueous sodium hydroxide solution or piperidine afforded the corresponding a,P-unsaturated ketones 56a-f in
80-88% yields (Scheme 23).


Other data

Title Synthesis of Some Modified Five and Six-membered Heterocyclic Rings with Expected Biological Activity
Other Titles تخليق بعض المشتقات الجديدة لحاقات خماسية وسداسية غير متجانسة معدلة ذات نشاط بيولوجى متوقع
Authors Eman Ramadan El-Sayed Kasem
Issue Date 2006

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