REMOVAL OF CERVICAL DISCHARGE BEFORE EMBRYO TRANSFER IN ICSI CYCLES RANDOMIZED CLINICAL TRIAL
Gehan Ahmed Abd Elgawad Omran;
Abstract
Recently, the techniques and variables affecting the success of embryo transfer have attracted more attention. Today more stress has been placed on optimizing and standardizing the embryo transfer protocol than ever before.
In order to ascertain the importance of each step involved in the embryo transfer procedure, individual factors must be evaluated independently. The removal of cervical mucus prior to embryo transfer has been suggested to directly influence the embryo implantation rates.
Cervical mucus has been postulated to interfere with proper embryo replacement. It has also been suggested that the presence of cervical mucous can prevent the embryos from leaving the catheter by acting as a ‘plug’ at the catheter tip. (Mansour and Aboulghar, 2002).
In addition, transferred embryos may stick to the cervical mucus around the catheter and be dragged from their original site of deposition during the withdrawal of the catheter.
Moreover, the mucus may also interfere with implantation if pushed or injected into the uterine cavity (Berkkanoglu et al., 2006).
Even so, if the cervical mucus is dragged into the endometrial cavity with the transfer catheter, cervical canal mucous may entangle the embryos, interfere with implantation and increase the risk of cervical expulsion of the embryos post-transfer (Nabi et al., 1997).
Another benefit of cervical cleaning and mucous removal is to reduce the risk of bacterial contamination of the catheter and endometrial cavity. Contamination of the catheter tip with micro-organisms such as streptococci (groups B and D), E. coli,staphylococci, mycoplasma and ureaplasma has been shown to reduce implantation and pregnancy rates (Salim et al., 2002).
The present study was a prospective case control study that was conducted at ART center maternity Hospital Ain Shams University.
A total number of 160 women was included in the study divided into two groups:
Group (1): The study group included 80 women from whom the cervical discharge was removed prior to embryo transfer by using insulin syringe.
In order to ascertain the importance of each step involved in the embryo transfer procedure, individual factors must be evaluated independently. The removal of cervical mucus prior to embryo transfer has been suggested to directly influence the embryo implantation rates.
Cervical mucus has been postulated to interfere with proper embryo replacement. It has also been suggested that the presence of cervical mucous can prevent the embryos from leaving the catheter by acting as a ‘plug’ at the catheter tip. (Mansour and Aboulghar, 2002).
In addition, transferred embryos may stick to the cervical mucus around the catheter and be dragged from their original site of deposition during the withdrawal of the catheter.
Moreover, the mucus may also interfere with implantation if pushed or injected into the uterine cavity (Berkkanoglu et al., 2006).
Even so, if the cervical mucus is dragged into the endometrial cavity with the transfer catheter, cervical canal mucous may entangle the embryos, interfere with implantation and increase the risk of cervical expulsion of the embryos post-transfer (Nabi et al., 1997).
Another benefit of cervical cleaning and mucous removal is to reduce the risk of bacterial contamination of the catheter and endometrial cavity. Contamination of the catheter tip with micro-organisms such as streptococci (groups B and D), E. coli,staphylococci, mycoplasma and ureaplasma has been shown to reduce implantation and pregnancy rates (Salim et al., 2002).
The present study was a prospective case control study that was conducted at ART center maternity Hospital Ain Shams University.
A total number of 160 women was included in the study divided into two groups:
Group (1): The study group included 80 women from whom the cervical discharge was removed prior to embryo transfer by using insulin syringe.
Other data
| Title | REMOVAL OF CERVICAL DISCHARGE BEFORE EMBRYO TRANSFER IN ICSI CYCLES RANDOMIZED CLINICAL TRIAL | Other Titles | تحسن معدلات الحمل بعد شفط إفرازات عنق الرحم قبل نقل الأجنة فى حالات الحقن المجهرى: دراسة عشوائية إكلينيكية | Authors | Gehan Ahmed Abd Elgawad Omran | Issue Date | 2016 |
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