STUDY OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE ENZYME DEFICIENCY AS A CAUSE OF NEONATAL JAUNDICE

Abstract

study of glucose-6-phosphate dehydrogenase enzyme deficiency as a cause of neonatal jaundice.Unpublished Master Thesis. Ain Shams University, Faculty of Science, Biochemistry Department, 1999. In this study sixty male mature neonates were classified into two groups,the first include neonates with normal bilirubin level (control group),the second group include neonates patients with hyperbilirubinemia,these were further subdivided into two subgroups, those with hyperbilirubinemia and normal glucose-6- phosphate dehydrogenase enzyme(group II a) and those with hyperbilirubinemia and glucose-6-phosphate dehydrogenase deficiency (group II b). By analyzing in detail the results of glucose-6-phosphate dehydrogenase deficient babies and excluding known causes for neonatal jaundice, and after correcting for the incidence of neonatal jaundice from unknown causes, we estimate that 26.67% of glucose-6-phosphate dehydrogenase deficient male newborns develop neonatal jaundice resulting from their enzyme deficiency.