THE RECENT MEDICAL AND NONINVASIVE TREATMENT OF PRIMARY OPEN ANGLE GLAUCOMA
Bahgat Zalwria Tawfik;
Abstract
POAG is the most prevalent of all glaucomas affecting
approximately 1 in 200 of the general population over the age
of 40 years and it is the third leading cause of blindness
worldwide. It is characterized by cupping and atrophy of the
optic disc, field loss, open angle and high lOP reflecting a
reduced aqueous humor outflow facility.
The major goal of glaucoma therapy is to lower the
intraocular pressure below the level that endangers the integrity
of the optic nerve. The treatment that achieves this goal, while
offering the lowest risk, fewest side effects and least disruption
of the patient's life, should be the one employed.
A series of topical CAIS have been developed and three
of these have undergone clinical trials. MK-927 was the first to
undergo extensive testing. This water soluble agent can be
prepared as a 2% solution. Other topical CAIS are MK-417 and
MK-507 which are closely related structurally to MK-927.
approximately 1 in 200 of the general population over the age
of 40 years and it is the third leading cause of blindness
worldwide. It is characterized by cupping and atrophy of the
optic disc, field loss, open angle and high lOP reflecting a
reduced aqueous humor outflow facility.
The major goal of glaucoma therapy is to lower the
intraocular pressure below the level that endangers the integrity
of the optic nerve. The treatment that achieves this goal, while
offering the lowest risk, fewest side effects and least disruption
of the patient's life, should be the one employed.
A series of topical CAIS have been developed and three
of these have undergone clinical trials. MK-927 was the first to
undergo extensive testing. This water soluble agent can be
prepared as a 2% solution. Other topical CAIS are MK-417 and
MK-507 which are closely related structurally to MK-927.
Other data
| Title | THE RECENT MEDICAL AND NONINVASIVE TREATMENT OF PRIMARY OPEN ANGLE GLAUCOMA | Authors | Bahgat Zalwria Tawfik | Issue Date | 2000 |
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