Minimally Invasive Surgical Approach Combined With Enamel Matrix Derivatives Versus Nano crystalline Hydroxyapatite In Treatment of Periodontal Intrabony defects : A Clinical,Radiographic, and Biochemical Study.

Abstract

Periodontitis is an inflammatory disease of the supporting tissues of the teeth, caused by a group of specific microorganisms; Periodontitis can result in bone resorption creating bony defects, which may cause tooth loss. Several treatment procedures have been studied to achieve periodontal regeneration.

A critical step in periodontal regenerative therapy is to alter the periodontitis affected root surface to make it a hospitable substrate, to support and encourage migration, attachment, proliferation and proper phenotypic expression of periodontal connective tissue progenitor cells. So the concept of EDTA root modification or alteration of the root surface has emerged as a potential therapeutic approach to the reconstruction of the periodontal unit.

Nanocrystalline hydroxyapatite is an alloplastic material chemically similar to the inorganic component of bone matrix and is known for its osteoinductive and osteoconductive properties in alveolar bone regeneration, NHA paste i