Physico-chemical studies on binary and ternary complexes of some transition metal ions. Investigation of their potential role in the catalysis of hydrolysis of amino acid esters

Abstract

This work has been carried out to investigate the synthesis and characterization of Pd(II) complexes with Picolylamine and the equilibria involved in the interaction of [Pd(pic)]2+ with 1,1-cyclobutane dicarboxylic acid and some biologically important ligands.The effect of chloride ion

concentration and the effect of solvent on the stability ofPd(Pic)-CBDCA complex are also reported. The palladium(II)-picolylamine complex promoted the hydrolysis of amino acid esters and the kinetic evidence of intermolecular mechanisms have been investigated. Also Ternary complexes of copper(II) involving picolylamine (Pic) and amino acids, peptides or DNA constitutents have been studied. The stability constants and concentration distribution as a function of pH of the complexes formed have been potentiometrically investigated. The kinetics of hydrolysis of amino acid esters coordinated to Cu(pici+ complex have also been studied.