PltospltodiAESTRASE INitibiToRs VERsus CATEcltolAMiNEs A CoMpARATivE HEModyNAMic STudy IN PATiENTs WiTit CiRculAToRy FAiluRE
Ashraf Mohe Al-Deen Nadim;
Abstract
Cardiovascular disease is the leading cause of death in the developed world today, its ultimate evolution is CHF is increasing in both incidence and prevelance.
End-stage heart failure has a poor prognosis , it impose a huge burden of mortality and morbidity ,this poor outcome can only be improved by cardiac transplantion. In those patients one the benefit from optimized therapy (diuretics ,digoxin and ACEinhibitors ) has been exhausted , only intravenous positive inotropic support can reverse the process of heart failure.
In this study 20 patients were symptomatic for more than 3 months inspite of maximum conventional anti-failure treatment (direutics, ACE inhbitors, digoxin and vasodilators).They were classsified according to their heart failure symptoms into (5 patients) in Class III and (15 patients) in class IV (NYHA) classification.
Patients presented with low cardiac output and hypotension, they were already on maximum anti-failure measures, They have very low expected survival rate. In such patients inotropic support essentially adrenergic agents i.e dobutamine is usually the agent of choice. So initiation of intravenous infusion of dobutamine was started with base line reading of complete hemodynamic monitoring using Swan-Ganz
End-stage heart failure has a poor prognosis , it impose a huge burden of mortality and morbidity ,this poor outcome can only be improved by cardiac transplantion. In those patients one the benefit from optimized therapy (diuretics ,digoxin and ACEinhibitors ) has been exhausted , only intravenous positive inotropic support can reverse the process of heart failure.
In this study 20 patients were symptomatic for more than 3 months inspite of maximum conventional anti-failure treatment (direutics, ACE inhbitors, digoxin and vasodilators).They were classsified according to their heart failure symptoms into (5 patients) in Class III and (15 patients) in class IV (NYHA) classification.
Patients presented with low cardiac output and hypotension, they were already on maximum anti-failure measures, They have very low expected survival rate. In such patients inotropic support essentially adrenergic agents i.e dobutamine is usually the agent of choice. So initiation of intravenous infusion of dobutamine was started with base line reading of complete hemodynamic monitoring using Swan-Ganz
Other data
| Title | PltospltodiAESTRASE INitibiToRs VERsus CATEcltolAMiNEs A CoMpARATivE HEModyNAMic STudy IN PATiENTs WiTit CiRculAToRy FAiluRE | Other Titles | دراسة مقارنة لعقارى مثبط الفوسفوداى استريز والكتيكولامين على مرضى هبوط الدورة الدموية | Authors | Ashraf Mohe Al-Deen Nadim | Issue Date | 2001 |
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