"Pain, Stress, Severity of Illness and Outcome In Ventilated Preterm Infants Physiological and Hormonal Indicators"

Hala Farag Abd El-Megeed Ahmed Marouf;

Abstract


Physiological and studied in 30 ventilated

hormonal pain and stress responses were
I
preterm infants admitted in the pediatric


intensive care unit of Cairo University Children's Hospital who were judged clinically to require sedation. Their mean gestational age was
34.4 ± 1.8 weeks (range: 30- 36). The sedation used was morphine.

Assessment of pain and distress in the preterm infants was tried in this study using (1) physiologic parameters (severity of illness parameters) in the form of vital signs assessment, ventilatory indices[oxygenation index, Pa02/PA02 and Pa02 / Fi02 j, Score for Neonatal Acute Physiology (SNAP) and Neonatal Theraputic Intervention Scoring System (NTISS); (2) Behavioral parameters
using different pain scoring systems as the Behavioral Pain Scale, Neonatal Infant Pain Score (NIPS), Comfort scale, Scale for Use in Newborn (SUN) and the Distress Scale for Ventilated Newborn Infants (DSVNI) (Lawrence ct al, 1993 & Ambuel et al, 1992 & Blauer and Gerstmann, 1998 & Pokela, 1994 and Sparshott, 1996 respectively); and (3) Hormonal parameters in the form of
concentrations of adrenaline, noradrenaline and cortisol levels in the

serum.

All pain scores and •ventilatory indices (oxygenation index, Pa02 /PA02 & Pa02 !Fi02) increased with the increase in the severity of illness assessed using SNAP and showed a positive correlation.
Responses were compared between infants with different clinical outcomes. Morphine reduced significantly the heart rate and respiratory rate (P < 0.05). Severity of illness as assessed by SNAP


Other data

Title "Pain, Stress, Severity of Illness and Outcome In Ventilated Preterm Infants Physiological and Hormonal Indicators"
Other Titles " دراسة عن الالم وشدة المرض ونتائجه فى الأطفال المبتسرين على جهاز التنفس الصناعي ومؤشراته الفسيولوجية والهرمونية "
Authors Hala Farag Abd El-Megeed Ahmed Marouf
Issue Date 2002

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