Role of Magnetic Resonance Spectroscopy Using Choline Peak as A Malignancy Marker In Diagnosis Of Suspicious Breast Lesions (BIRADS III and IV)

Abstract

Abstract Background: BIRADS III and IV lesions are a clinical dilemma as they need either follow up or biopsy. Since 80% of lesions determined in the breast are benign upon biopsy, we need new methods for evaluation of these lesions to avoid unnecessary breast interventions. MR spectroscopy is a promising new technique which can be used to improve the diagnosis of breast lesions classified according to BIRADS category. The diagnostic value of H-MRS is typically based on the elevation of choline compounds which are the markers of malignancy and aid in the differentiation between benign and malignant breast lesions. Aim of the Work: To assess the diagnostic value of MR spectroscopy using choline peak as a malignancy marker in diagnosis of suspicious breast lesions categorized by mammography or sonomamography as (BIRADS III, IV) and correlation with available histopathological findings, clinical data or follow up.