Hysteroscopic Tubal Occlusion Using Iso-Amyl 2-Cyano Acrylate (Amcrylate) in Patients with Hydrosalpinx

Abstract

his is a pilot study conducted in the Early Cancer Detection Unit of the Ain Shams University Maternity and Women’s Hospital, Abbasseyah – Cairo, Egypt in the period from July 2015 to February 2018. It included twenty patients who needed tubal block for hydrosapinx prior ICSI/IVF. The patients participating in the study were subjected to hysteroscopic tubal cannulation at the uterotubal junction with unilateral instillation of 0.5 ml. of an adhesive material: Isoamyl 2 cyanoacrylate (Amcrylate®). Then follow up by hystrosaqlpingeogram after 3 month later to detect closure of the tube after. The aim of the study was to test the safety of the material and its effectiveness on effecting tubal occlusion. The material used proved to be safe as evidenced by clinical, laboratory and histopathological findings. The procedure was relatively easy to perform and learn. There was minimal discomfort to the patients and no patients asked to interrupt the procedure for any reason. The procedure was 88.9% effective if we take into consideration a result of hystrosalpigeogram showed completely occlude tube. The small number of patients participating in the study might have hindered the proper.