MAGNETIC RESONANCE SPECTROSCOPY IN EVALUATION OF MULTIPLE SCLEROSIS

Abstract

MS is a diffuse dynamic disease that evolves over time; it’s characterized by the presence of CNS lesions disseminated in space and time. MS is an immune-mediated inflammatory demyelinating disease of the central nervous system clinically characterized by relapses and remissions of neurological disturbance. It expresses itself in four clinical forms: relapsing remitting MS (RRMS), secondary progressive MS (SPMS), primary progressive MS (PPMS), and progressive relapsing MD (PRMS). Plaques of inflammatory demyelination within the CNS are the pathologic hallmark of MS. MS is a chronic and somewhat unpredictable disease comprising different disease types, ranging from a mild, benign course associated with little disability to a chronic progressive course with rapidly accumulating disability, the clinical course of MS is quite variable and is very hard to predict for an individual patient. Most neurologists are familiar with the common clinical features of multiple sclerosis (MS), which have been reviewed by numerous authors.