Total Nucleated cell count in umbilical cord blood of preterm delivery
Ehab Abdallah Mohamed Salem;
Abstract
The current study aimed to clarify the impact of maternal and neonatal factors on total nucleated cell count of collected umbilical cord blood of preterm delivery < 36 weeks completed gestation.
Methodology
This cross sectional study included 40 newborns; 20 (50%) were males and 20 (50%) were females, with GA of 32.77±2.485 weeks, birth weight 2120.83±500.862 gm, length 43.95±2.396 cm and OFC was 32.07±1.558 cm. The APGAR score at 1 min ranged between 4-8 with median 6, while at 5 min it ranged between 7-9 with median 8.
Comprehensive history taking was done for all stressing on: Pre-existing maternal problems; Fetal problem: and Natal history.
Detailed clinical neonatal examination :Determination of the gestational age using Ballard score , APGAR score at 1 & 5 minutes, Determination of birth weight, length and occipito-frontal circumference and Cord and Placental examination and weight.
Collection of cord blood : Two methods for collection of umbilical cord blood were included: method 1, collection with a blood bag; method 2, syringe-assisted and drain with an open sterile container.
Laboratory investigations: maternal and neonatal ABO and Rh blood group, CBC and TNC counting .
Results
Among the 40 newborns 20 (50%) were males and 20 (50%) were females, with GA of 32.77±2.485 weeks, birth weight 2120.83±500.862 gm, length 43.95±2.396 cm and OFC was 32.07±1.558 cm. The APGAR score at 1 min ranged between 4-8 with median 6, while at 5 min it ranged between 7-9 with median 8.
Maternal age was 27.37±1.41 years and ranged between 25-30 years, mother weight ranged between 70-85 kg with mean±SD of 77.85±3.73, mother Hb% ranged between 11-13.5 % with mean±SD of 12.10±0.79, placental weight was 496.352±80.672 gm and cord length was 52.3± 110.7 cm. Seven neonates (17.5%) delivered vaginally while 33 (82.5%) delivered by CS, 7 (17.5%) had no anesthesia, 20 (50%) had spinal anesthesia and 13(32.5%) had general anesthesia. Regarding resuscitation, O2 was used in 13 (32.5%) neonates while 27 (67.5%) neonates did not need O2 during resuscitation. Thirteen (32.5%) cord blood samples were collected using Bag and 27 (67.5%) samples were collected using syringe. No cord anomilies was detected in this study.
Regarding maternal factors, 6 (15%) mothers had hypertension while only 4 (10%) had preeclampsia, 6 (15%) had gestational DM, 12 (30%) had PROM and all of them did not have fever during that pregnancy.
Methodology
This cross sectional study included 40 newborns; 20 (50%) were males and 20 (50%) were females, with GA of 32.77±2.485 weeks, birth weight 2120.83±500.862 gm, length 43.95±2.396 cm and OFC was 32.07±1.558 cm. The APGAR score at 1 min ranged between 4-8 with median 6, while at 5 min it ranged between 7-9 with median 8.
Comprehensive history taking was done for all stressing on: Pre-existing maternal problems; Fetal problem: and Natal history.
Detailed clinical neonatal examination :Determination of the gestational age using Ballard score , APGAR score at 1 & 5 minutes, Determination of birth weight, length and occipito-frontal circumference and Cord and Placental examination and weight.
Collection of cord blood : Two methods for collection of umbilical cord blood were included: method 1, collection with a blood bag; method 2, syringe-assisted and drain with an open sterile container.
Laboratory investigations: maternal and neonatal ABO and Rh blood group, CBC and TNC counting .
Results
Among the 40 newborns 20 (50%) were males and 20 (50%) were females, with GA of 32.77±2.485 weeks, birth weight 2120.83±500.862 gm, length 43.95±2.396 cm and OFC was 32.07±1.558 cm. The APGAR score at 1 min ranged between 4-8 with median 6, while at 5 min it ranged between 7-9 with median 8.
Maternal age was 27.37±1.41 years and ranged between 25-30 years, mother weight ranged between 70-85 kg with mean±SD of 77.85±3.73, mother Hb% ranged between 11-13.5 % with mean±SD of 12.10±0.79, placental weight was 496.352±80.672 gm and cord length was 52.3± 110.7 cm. Seven neonates (17.5%) delivered vaginally while 33 (82.5%) delivered by CS, 7 (17.5%) had no anesthesia, 20 (50%) had spinal anesthesia and 13(32.5%) had general anesthesia. Regarding resuscitation, O2 was used in 13 (32.5%) neonates while 27 (67.5%) neonates did not need O2 during resuscitation. Thirteen (32.5%) cord blood samples were collected using Bag and 27 (67.5%) samples were collected using syringe. No cord anomilies was detected in this study.
Regarding maternal factors, 6 (15%) mothers had hypertension while only 4 (10%) had preeclampsia, 6 (15%) had gestational DM, 12 (30%) had PROM and all of them did not have fever during that pregnancy.
Other data
| Title | Total Nucleated cell count in umbilical cord blood of preterm delivery | Other Titles | اجمالى عد الخلايا ذات الأنوية في دم الحبل السري للولادة المبكرة | Authors | Ehab Abdallah Mohamed Salem | Issue Date | 2014 |
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