THE PROTECTIVE EFFECT OF AN ISOTHIOCYANATE PRODRUG AGAINST CHROMOSOMAL ABERRATIONS INDUCED BY SOME MUTAGENIC DRUGS IN MICE

Abstract

During recent years, considerable efforts have been focused on using antimutagens or anticarcinogens modulate the genotoxic effects of different mutagenic drugs. So, many experiments are currently underway in order to detect agents which can suppress cellular mutagenesis and carcinogenesis. All these experiments were based on the principle of adding the substance to be tested for antimutagenic effect to a known mutagen in• the respective test system.