Deep endotracheal aspirate versus nonbronchoscopic bronchoalveolar lavage for diagnosing ventilator-associated pneumonia in newborns

Abstract

The current study was done in order to compare and determine the effectiveness of deep endotracheal aspiration versus non-broncoscopic- broncholveolar lavage in diagnosing ventilator- associated pneumonia (VAP) in newborns. This study was conducted in the Neonatal Intensive Care Unit (NICU), Faculty of medicine Ain-Shams university and Elshohada NICU and included 50 newborns on mechanical ventilation for more than 48 hours with clinical suspicion of VAP. For all included newborns full medical history was taken, thorough clinical examination was done together with CBC, CRP, blood culture, and Chest X-ray PA view. In addition both of tracheal aspirate and non bronchoscopic bronchoalveolar lavage were done for all included newborns and processed for microbiological examination including quantitative – culture, microscopic quantitative friction of PMNs containing intracellular bacteria and gram stain. The results of the present study showed that there was mild agreement of QDEA and the NB-BAL at cutoff of (> or = 104 cfu/ml) in diagnosis of VAP in mechanically