Effect of Dexamethasone on Daily Fetal Movement, Umbilical and Middle Cerebral Arteries Doppler and Cardiotocogram
Nader Mohamed Ibrahim;
Abstract
SUMMARY
P
rematurity complications have been a timeless problem and a cause of death among live born infants, especially the problems concerning lung maturity and pulmonary surfactant formation.
Steroids’ use has been acknowledged as a way to prevent many of the complications, such as intraventricular haemorrhage, and the pulmonary complications, such as respiratory distress syndrome.
The use of steroids, namely Dexamethasone, has been speculated to cause some clinical side effects, along with some physiological alterations, and several studies have been conducted to detect them. Some of these effects are the influence of steroids on Doppler arterial velocity waveforms, biophysical profile, daily foetal movement count, and cardiotocography.
In our study, we selected 110 women with no foetal risk, with gestational age at term, and gave them a single course of Dexamethasone, consisting of 4 doses of 6 mg.
All women were subjected to the following before the administration, and 24 to 48 hours after the last dose, specifically between the 60th and the 72nd hours:
Doppler waveform velocities of the UA and the MCA represented by the PI and RI.
20 minutes cardiotocography nonstress test trace.
P
rematurity complications have been a timeless problem and a cause of death among live born infants, especially the problems concerning lung maturity and pulmonary surfactant formation.
Steroids’ use has been acknowledged as a way to prevent many of the complications, such as intraventricular haemorrhage, and the pulmonary complications, such as respiratory distress syndrome.
The use of steroids, namely Dexamethasone, has been speculated to cause some clinical side effects, along with some physiological alterations, and several studies have been conducted to detect them. Some of these effects are the influence of steroids on Doppler arterial velocity waveforms, biophysical profile, daily foetal movement count, and cardiotocography.
In our study, we selected 110 women with no foetal risk, with gestational age at term, and gave them a single course of Dexamethasone, consisting of 4 doses of 6 mg.
All women were subjected to the following before the administration, and 24 to 48 hours after the last dose, specifically between the 60th and the 72nd hours:
Doppler waveform velocities of the UA and the MCA represented by the PI and RI.
20 minutes cardiotocography nonstress test trace.
Other data
| Title | Effect of Dexamethasone on Daily Fetal Movement, Umbilical and Middle Cerebral Arteries Doppler and Cardiotocogram | Authors | Nader Mohamed Ibrahim | Issue Date | 2018 |
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