Measurement of Soluble Transferrin Receptors In Iron Deficiency Anemia And Anemia of Chronic Diseases
Ashraf Kamal Abd-Elhamid;
Abstract
Soluble Transferrin receptor is a promising tool to detect iron status and to differentiate between iron deficiency anemia and anemia of chronic diseases as the concentration of sTfR is, in contrast to ferritin level, not influenced by the acute phase response.
The concentration of sTfR provides a useful quantitative measure of the erythroid marrow mass, and thereby assists in categorizing the types of anemia.
Furthermore, a most important clinical use of sTfR IS determining the Cause Of Iron deficient erythropoiesis (that IS identifYing iron deficient anemia whether it occurs alone or in the presence of anemia of chronic disease).
In current study it was found that serum ferritin level in ACD group was significantly increased when compared to the control group while the mean level of serum ferritin in IDA group was • significantly decreased when compared with control group.
sTfR mean levels recorded in this study, were found to show significant increase in the IDA group when cmnpared to the controls. This reflects a response to the cells obligate need for iron. The mean level of sTfR in the ACD group was significantly lower than that of the control group.
The concentration of sTfR provides a useful quantitative measure of the erythroid marrow mass, and thereby assists in categorizing the types of anemia.
Furthermore, a most important clinical use of sTfR IS determining the Cause Of Iron deficient erythropoiesis (that IS identifYing iron deficient anemia whether it occurs alone or in the presence of anemia of chronic disease).
In current study it was found that serum ferritin level in ACD group was significantly increased when compared to the control group while the mean level of serum ferritin in IDA group was • significantly decreased when compared with control group.
sTfR mean levels recorded in this study, were found to show significant increase in the IDA group when cmnpared to the controls. This reflects a response to the cells obligate need for iron. The mean level of sTfR in the ACD group was significantly lower than that of the control group.
Other data
| Title | Measurement of Soluble Transferrin Receptors In Iron Deficiency Anemia And Anemia of Chronic Diseases | Other Titles | قياس مستقبلات الترانسفرين الذائبة فى انيميا نقص الحديد وانيميا الامراض المزمنة | Authors | Ashraf Kamal Abd-Elhamid | Issue Date | 2002 |
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