TANDEM IN SITU SYNTHESIS AND REARRANGEMENT OF CERTAIN HYDRAZONATE ESTERS
Thoraya Abd El Reheem Farghaly Mohamed;
Abstract
The first part of the original work of the thesis outlines a facile one pot regioselective synthesis of [I ,2,4]triazolo[4,3-a]-5(1 H)-pyrimidinones via tandem Japp-Kiingemann, Smiles rearrangement and cyclization
reactions by azo coupling of various diazonium salts with the respective
I substitution products obtained from reaction of6-phenyl-2-thiouracil with ,
some active chloromethylene compounds.
The second part deals with synthesis offunctionalized derivatives of novel pentaheterocyclic ring system namely pyrido[2,3-f: 6,5-f •]di- [1 ,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one. The synthetic strategy is based
1 on
reaction odf hy_drazonoyl haflid es witdh dpyridodipy •imbidi nes. Th e .
mec 1hanisms an regiochemistry of the studies reactions in both resesrch
projects were discussed.
reactions by azo coupling of various diazonium salts with the respective
I substitution products obtained from reaction of6-phenyl-2-thiouracil with ,
some active chloromethylene compounds.
The second part deals with synthesis offunctionalized derivatives of novel pentaheterocyclic ring system namely pyrido[2,3-f: 6,5-f •]di- [1 ,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one. The synthetic strategy is based
1 on
reaction odf hy_drazonoyl haflid es witdh dpyridodipy •imbidi nes. Th e .
mec 1hanisms an regiochemistry of the studies reactions in both resesrch
projects were discussed.
Other data
| Title | TANDEM IN SITU SYNTHESIS AND REARRANGEMENT OF CERTAIN HYDRAZONATE ESTERS | Other Titles | الاصطناع والتعديل الجزيئي المتتابعان داخليا لبعض أسترات هيدرازونوات | Authors | Thoraya Abd El Reheem Farghaly Mohamed | Issue Date | 2001 |
Attached Files
| File | Size | Format | |
|---|---|---|---|
| B11478.pdf | 976.74 kB | Adobe PDF | View/Open |
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.