Histo-pathology in Pre - and Post- menopausal Bleeding Correlation of Ultrasound Findings and Endometrial

Abstract

This study was designed to evaluate the role of ultrasonography as a diagnostic and screening investigation to detect endometrial pathology in cases with premenopausal or postmenopausal bleeding.

To fulfill this aim, 30 women with premenopausal bleeding and 20 women With postmenopausal bleeding were examined ultrasonographically before undergoing D & C or hysterectomy operations in the Gynaecology Department of Ain Shams University Hospital. The endometrial thickness was measured in both longitudinal and transverse sections of the uterus, the average endometrial thickness was then calculated. Histopathologic examination was carried out for the specimens recovered from D & C and hysterectomy operations. The results of ultrasonography and histopathology were examined statistically.

From this study, we found that ultrasonography can be used diagnostically and as a screening method to detect endometrial pathology in cases with postmenopausal bleeding. Using 5 mm thickness of endometrium is found to be an appropriate cutoff limit below which endometrial pathology can be excluded in such cases.

Although in cases with premenopausal bleeding the results came in agreement with previous studies in that an endometrial thickness of 8 mm can be used as a cutoff limit, below which endometrial pathology is excluded, yet, these studies are not enough to extrapolate a relationship between the ultrasonographic findings and histopathology upon which ultrasonogarphy is used diagnostically or as screening investigation for endometrial pathology in premenopausal women.