Nutritional Assessment of Children with Refractory Epilepsy in Ain Shams Neurology Clinic
Rehab Yehia Sayed Mohamed;
Abstract
SUMMARY
O
ur scope was to assess the nutritional status of children with idiopathic refractory epilepsy.
This study was conducted in Ain Shams University Hospitals, Pediatric Neurology Clinic, on 300 children aged from 2 to 16 years who were comprised in 2 groups as follows:
Group 1 (cases):
One hundred fifty children with idiopathic refractory epilepsy recruited from the Pediatric Neurology Clinic. They were 89 males and 61 females and a mean age of 7.77± 2.97 years, in a period from January 2015 to December 2015.
The patients were subdivided according to the AEDS given into 2 subgroups:-
Subgroup1: comprised 130 patients who were receiving VPA at the dose (28.77±11.39) mg/kg/day.
Subgroup 2: comprised 20 patients who were receiving Non VPA as Carbamazepine at the dose (24.93±11.56) mg/kg/day, Levetiracetam at the dose (17.15±8.52) mg/kg/day, Topiramate at the dose (6.46±1.29) mg/kg/day and Lamotrigene at the dose (1.98±0.83) mg/kg/day.
Group 2 (control group):
One hundred fifty apparently normal children (80 males and 70 females) with a mean age of 7.32± 2.97, they were recruited from the siblings of children attending the Outpatients' Clinic.
The patients and controls were subdivided into 3 subgroups according to their ages:
Subgroup (1) from 2-5 years.
Subgroup (2) from 6-12 years.
Subgroup (3) from 13-16 years.
The results of our study revealed:
Patients had significantly higher weight, height, BMI, mid arm circumference, triceps skin fold thickness with their z score in comparison to the control.
Patients receiving valproate had significantly higher z-weight, z-BMI, Z-mid arm circumference, body fat, fat free mass, muscle mass and body water in comparison to controls.
In food composition analysis in age group from 2-5 years, patients had higher fat but control group had elevated caloric intake, protein, fiber, carbohydrate, sodium, potassium, iron and zinc in comparison to patients.
In food composition analysis in age group from 6-12 years, patients had elevated fat, phosphorus, magnesium, iron and vitamin B2 in comparison to control group.
In food composition analysis in age group from 13-16 years, there was no significant difference between patients and controls.
There was a positive significant correlation between age of onset of epilepsy and caloric intake, protein, fiber, C
O
ur scope was to assess the nutritional status of children with idiopathic refractory epilepsy.
This study was conducted in Ain Shams University Hospitals, Pediatric Neurology Clinic, on 300 children aged from 2 to 16 years who were comprised in 2 groups as follows:
Group 1 (cases):
One hundred fifty children with idiopathic refractory epilepsy recruited from the Pediatric Neurology Clinic. They were 89 males and 61 females and a mean age of 7.77± 2.97 years, in a period from January 2015 to December 2015.
The patients were subdivided according to the AEDS given into 2 subgroups:-
Subgroup1: comprised 130 patients who were receiving VPA at the dose (28.77±11.39) mg/kg/day.
Subgroup 2: comprised 20 patients who were receiving Non VPA as Carbamazepine at the dose (24.93±11.56) mg/kg/day, Levetiracetam at the dose (17.15±8.52) mg/kg/day, Topiramate at the dose (6.46±1.29) mg/kg/day and Lamotrigene at the dose (1.98±0.83) mg/kg/day.
Group 2 (control group):
One hundred fifty apparently normal children (80 males and 70 females) with a mean age of 7.32± 2.97, they were recruited from the siblings of children attending the Outpatients' Clinic.
The patients and controls were subdivided into 3 subgroups according to their ages:
Subgroup (1) from 2-5 years.
Subgroup (2) from 6-12 years.
Subgroup (3) from 13-16 years.
The results of our study revealed:
Patients had significantly higher weight, height, BMI, mid arm circumference, triceps skin fold thickness with their z score in comparison to the control.
Patients receiving valproate had significantly higher z-weight, z-BMI, Z-mid arm circumference, body fat, fat free mass, muscle mass and body water in comparison to controls.
In food composition analysis in age group from 2-5 years, patients had higher fat but control group had elevated caloric intake, protein, fiber, carbohydrate, sodium, potassium, iron and zinc in comparison to patients.
In food composition analysis in age group from 6-12 years, patients had elevated fat, phosphorus, magnesium, iron and vitamin B2 in comparison to control group.
In food composition analysis in age group from 13-16 years, there was no significant difference between patients and controls.
There was a positive significant correlation between age of onset of epilepsy and caloric intake, protein, fiber, C
Other data
| Title | Nutritional Assessment of Children with Refractory Epilepsy in Ain Shams Neurology Clinic | Other Titles | التقييم التغذوي للأطفال المصابين بالصرع المقاوم للأدوية بعيادة الأعصاب بمستشفى الأطفال – جامعة عين شمس | Authors | Rehab Yehia Sayed Mohamed | Issue Date | 2016 |
Attached Files
| File | Size | Format | |
|---|---|---|---|
| G11616.pdf | 249.08 kB | Adobe PDF | View/Open |
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