Vascular cell adhesion molecules-1 In pre-eclampsia

Abstract

The current evidence• in medical literature point out that elevated soluble vascular cell-adhesion molecules (sVCAM) can be of a high predictive value of the severity of pre­ eclampsia and its possible consequences to the products of conception (Lyall et al. 1994)

This study a prospective case-control study designed to correlate between soluble form of vascular cell adhesion molecules-! (sVCAM-1) and different degrees of pre­ eclampsia as well as its possible consequences on fetal growth.

Forty-two third trimester primigravid women with various degrees of pre-eclampsia [mild (22) & severe (20)] were recruited for this study, and compared wilh 20 healthy primi-gravid women with uncomplicated pregnancies as regard their age, gestational age, foetal birth weight, placental weight and the incidence of abnormal gross placental morphology, these results were correlated to sVCAM-llevel.

The results of this study showed no difference between