PARATHYROID HORMONE - RELATED PROTEIN IN TRACHEAL SPIRATES OF NEWBORN INFANTS

Abstract

Statistical analysis of the obtained clinical and laboratory data showed that : • The mean of gestaional age and birth weight show a highly significant increase in full term neonates when compared to preterm neonates. • The degree of respiratory distress as evaluated by silverman score was significantly lower in full terms when compared to preterms. • • Regarding the heamatological parameters we found that TLC was significantly higher in fullterm neonates compared to preterm neonates. • The level of PTHrp in the tracheal aspirates of full term infants was found to be higher than the level in tracheal aspirates of preterm neonates. • Among the full term neonates, CRP positive neonates show a non significant decrease in the level of PTHrp when compared to CRP negative neonates. • Among the preterm neonates, CRP positive neonates show a non significant increase in the level of PTHrp when compared to CRP negative neonates. • A postive significant correlation between the level of

PTHrp in tracheal of all patients and their gestational age and birth weight:

Finally, we concluded that PTHrp in tracheal aspirate of newborn i?fants could be used as a parameter for neonatal lung maturation.