COMPARISON OF NON-INVASIVE METHODS FOR DISTINGUISHING STEROID SENSITIVE AND STEROID 'RESISTANT NEPHROTIC SYNDROME
NUHAIR MAHROUS ABDEL-WAHED;
Abstract
Nephrotic syndrome (NS) is one of the commonest renal diseases m childhood and hence its diagnosis and follow up is important for any practicing pediatrician.
The aim of the work was to use simple, non-mvas1ve and
relatively cheap methods to predict the response to steroids and the underlying renal histologic diagnosis inNS and which will be useful for monitoring progress.
For this purpose, the 24 hour urinary protein estimate9 by the routine collection method with the new method of diagnosis of proteinuria by estimating protein/creatinine ratio in spot urine sample were compared. The results revealed that there was no significant difference between the two methods and urinary protein/creatinine ratio can be used as a reliable and accurate method for diagnosis, prognosis and follow up of all degrees of proteinuria.
The use of selectivity index (SI) as a non-invasive test for
differentiation between steroid sensitive and steroid resistant NS was studied. SI can be used to shorten the duration of steroid therapy in patients who are unlikely to be steroid sensitive.
The aim of the work was to use simple, non-mvas1ve and
relatively cheap methods to predict the response to steroids and the underlying renal histologic diagnosis inNS and which will be useful for monitoring progress.
For this purpose, the 24 hour urinary protein estimate9 by the routine collection method with the new method of diagnosis of proteinuria by estimating protein/creatinine ratio in spot urine sample were compared. The results revealed that there was no significant difference between the two methods and urinary protein/creatinine ratio can be used as a reliable and accurate method for diagnosis, prognosis and follow up of all degrees of proteinuria.
The use of selectivity index (SI) as a non-invasive test for
differentiation between steroid sensitive and steroid resistant NS was studied. SI can be used to shorten the duration of steroid therapy in patients who are unlikely to be steroid sensitive.
Other data
| Title | COMPARISON OF NON-INVASIVE METHODS FOR DISTINGUISHING STEROID SENSITIVE AND STEROID 'RESISTANT NEPHROTIC SYNDROME | Other Titles | الوسائل اللاتداخلية للتفرقة بين التورم النفروزى المستجيب للكورتيزون والمقاوم للكورتيزون | Authors | NUHAIR MAHROUS ABDEL-WAHED | Issue Date | 2001 |
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