FIBRINOGEN AS A RISK FACTOR OF CORONARY HEART DISEASE
SALWA SUWAILLAM;
Abstract
Coronary heart disease is one of the most important causes of death all-over the world. It is mainly caused by thickening of the inside walls of the coronary arteries. This thickening is called atherosclerosis.
The lesion of atherosclerosis reveal that each lesion contains the elements of an inflammatory response together with varying levels of fibrinoproliferative response.
Fibrinogen is a blood protein that has a critical role in coagulation process in the body. During coagulation, fibrinogen reacts with thrombin to produce fibrin, which in turn produces insoluble fibrin network. Fibrinogen also promotes platelet aggregation and thrombus formation at an atherosclerotic plaque.
This study was a case-control study, which aimed to find out the relatioship between plasma fibrinogen level and ischemic heart disease. In other words, can fibrinogen be considered as an independent risk factor for the development of IHD?
This study include 53 patients, 33 ischemic patients and 20 normal controls. The mean age in the ischemic group was 50.2 ± 7.8 years, while the mean age of the control group was 52.0 ± 11.1 years.
The lesion of atherosclerosis reveal that each lesion contains the elements of an inflammatory response together with varying levels of fibrinoproliferative response.
Fibrinogen is a blood protein that has a critical role in coagulation process in the body. During coagulation, fibrinogen reacts with thrombin to produce fibrin, which in turn produces insoluble fibrin network. Fibrinogen also promotes platelet aggregation and thrombus formation at an atherosclerotic plaque.
This study was a case-control study, which aimed to find out the relatioship between plasma fibrinogen level and ischemic heart disease. In other words, can fibrinogen be considered as an independent risk factor for the development of IHD?
This study include 53 patients, 33 ischemic patients and 20 normal controls. The mean age in the ischemic group was 50.2 ± 7.8 years, while the mean age of the control group was 52.0 ± 11.1 years.
Other data
| Title | FIBRINOGEN AS A RISK FACTOR OF CORONARY HEART DISEASE | Other Titles | الفيبرينوجين وزيادة احتمالات الاصابة بأمراض الشرايين التاجية | Authors | SALWA SUWAILLAM | Issue Date | 2002 |
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