Role of the First Trimester Maternal Serum High Sensitivity C–Reactive Protein and Second Trimester Placental Volume Measurement and vascularization by 3D Doppler Ultrasound in Early Detection of Pre-Eclampsia

Abstract

in Ain Shams maternity University hospital. The objective of this study was to evaluate the ability of first trimester serum level of HsCRP of pregnant women and the ability of 3D-placental volume and vascular flow indices to predict preeclampsia. We started with 230 pregnant women and they were subjected to the inclusion and exclusion criteria, after exclusion of pregnant women not fulfilling inclusion criteria we had 222 women and 7 of them had aborted by end of first trimester lastly 15 pregnant women had escaped study so we resumed study having 200 pregnant women. At 1st trimesteric serum level of HsCRP was detected, at 2nd trimesterthe volume of the placenta and vasularization indices of placenta were measured with a 3D transabdominal ultra-sound transducer by multiple operators. The results revealed that HsCRP was was significantly (P≤ 0.05 and 0.01) high in Pre-eclampsia group than the