Serum Magnesium and Calcium Levels in Preeclamptic Women
Reham Fekry Swellam Ali;
Abstract
Preeclampsia, also known as toxemia, is a serious complication of pregnancy. It is the biggest single cause of maternal and fetal mortality and currently there is no cure other than termination of pregnancy.
Preeclampsia occurs in approximately 3 to 14 percent of all pregnancies worldwide and about 5 to 8 percent in the United States. The disease is mild in 75 percent of cases in the United States, and severe in 25 percent. Ten percent of preeclampsia occurs in pregnancies less than 34 weeks of gestation.
Sixty women during the third trimester were included in this study and divided into the following:
Group 1 (Control group); included 30 females with normal uncomplicated pregnancy
Group 2 (pre-eclamptic group), included 30 females with pre-eclampsia, which is further divided into:
o Group A: Mild pre-eclampsia, included 15 females
o Group B: Severe pre-eclampsia, included 15 females.
The diagnosis of mild preeclampsia:
Was based on the findings of elevation of blood pressure of 140/90 mmHg (on two occasions at least 6 hours apart) which was accompanied by proteinuria (0.3 g protein/24 hours collected urine or ≥ +2 by dipstick) and edema[41].
Criteria for defining sever preeclampsia :
Was elevated blood pressure ≥160/100 mmHg, proteinuria ≥5g protein/24 hours collecting urine or ≥++ by dipstick, or presence of headache, visual disturbances, epigastric pain, IUGR, elevated liver enzymes, or low platelets[41].
Our exclusive criteria will be:
1) Multiparty.
2) Gestational age less than 26 weeks.
3) Multiple gestations.
4) Evidence of anemia or systemic infection.
5) History of chronic hypertension or renal disease.
6) History of cardiovascular disease.
7) Urinary tract infection.
8) Diabetes Mellitus.
Every subject will be subjected to:
1) Verbal consent.
2) Complete history to asses severity of preeclampsia and to exclude history of chronic hypertension, renal disease or blood transfusion. 3) General examination of the patients including pulse, and blood pressure to diagnose preeclampsia.
4) Abdominal examination including size of uterus, and epigastric tenderness to asses severity of preeclampsia.
5) Collection of: Clean catch random urinary specimen to determine proteinuria by urinary dipstick.
6) Withdrawal of venous sample for measurement of :
A-Complete blood count.
B-Renal function test.
C-Serum Magnesium and Calcium levels by ELISA technique.
Preeclampsia occurs in approximately 3 to 14 percent of all pregnancies worldwide and about 5 to 8 percent in the United States. The disease is mild in 75 percent of cases in the United States, and severe in 25 percent. Ten percent of preeclampsia occurs in pregnancies less than 34 weeks of gestation.
Sixty women during the third trimester were included in this study and divided into the following:
Group 1 (Control group); included 30 females with normal uncomplicated pregnancy
Group 2 (pre-eclamptic group), included 30 females with pre-eclampsia, which is further divided into:
o Group A: Mild pre-eclampsia, included 15 females
o Group B: Severe pre-eclampsia, included 15 females.
The diagnosis of mild preeclampsia:
Was based on the findings of elevation of blood pressure of 140/90 mmHg (on two occasions at least 6 hours apart) which was accompanied by proteinuria (0.3 g protein/24 hours collected urine or ≥ +2 by dipstick) and edema[41].
Criteria for defining sever preeclampsia :
Was elevated blood pressure ≥160/100 mmHg, proteinuria ≥5g protein/24 hours collecting urine or ≥++ by dipstick, or presence of headache, visual disturbances, epigastric pain, IUGR, elevated liver enzymes, or low platelets[41].
Our exclusive criteria will be:
1) Multiparty.
2) Gestational age less than 26 weeks.
3) Multiple gestations.
4) Evidence of anemia or systemic infection.
5) History of chronic hypertension or renal disease.
6) History of cardiovascular disease.
7) Urinary tract infection.
8) Diabetes Mellitus.
Every subject will be subjected to:
1) Verbal consent.
2) Complete history to asses severity of preeclampsia and to exclude history of chronic hypertension, renal disease or blood transfusion. 3) General examination of the patients including pulse, and blood pressure to diagnose preeclampsia.
4) Abdominal examination including size of uterus, and epigastric tenderness to asses severity of preeclampsia.
5) Collection of: Clean catch random urinary specimen to determine proteinuria by urinary dipstick.
6) Withdrawal of venous sample for measurement of :
A-Complete blood count.
B-Renal function test.
C-Serum Magnesium and Calcium levels by ELISA technique.
Other data
| Title | Serum Magnesium and Calcium Levels in Preeclamptic Women | Other Titles | نسبة الماغنسيوم و الكالسيوم لدى السيدات المصابين بتسمم الحمل | Authors | Reham Fekry Swellam Ali | Issue Date | 2014 |
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