Identification of Certain Pharmaceutical Compounds Using Different Spectroscopic and Chromatographic Techniques

Abstract

This thesis deals with the identification and determination of some APis, their degradation products preservatives and sweetening agents using spectrophotometry and hyphenated high performance liquid chromatography with photodiode array detectors

The thesis comprises three sections

Section 1: General introduction

This section contains an introduction about the chemical names, structures and physical properties of the studied drugs, preservatives and sweetening agents; it contains an introduction about the chemical names and structures of the main degradation products of the investigated drugs. It also contains literature reviews for the reported methods of analysis for the selected drugs in their pharmaceutical dosage forms as well as biological fluids. This section also describes the analytical methods used in this thesis including spectrophotometry and high performance liquid chromatography.