STUDY OF CLINICAL AND DIAGNOSTIC DATA IN PATIENTS WITH LUNG CANCER AT ABBASSIA CHEST HOSPITAL FROM JANUARY 2010 TO DECEMBER 2013
Basma Malak Zaki;
Abstract
The current study was conducted at Abbasia Chest Hospital from January 2010 to December 2013 to study pattern of lung cancer on 800 patients admitted in that period.
All Patients underwent Full history taking with special emphasize on smoking history including smoking state. clinical examination including both general &local examination of the chest, radiological examination including plain chest x-ray posteroanterior view, Computed Tomography of the chest , methods of diagnosis and tools of getting tissue biopsy for confirmatory diagnosis.
There were 800 patients with lung cancer adenocrcinoma was 298 (37.25%), squamous cell carcinoma 196 (24.50%) , small cell carcinoma 171(21.38%), large cell carcinoma 99 (12.38%), 25 metastasis (3.13%) and others 11 (1.38%) including other types of bronchogenic carcinoma and non conclusive ones.
The statistical analysis and differences included 764 subject only excluding (metastasis and other types) because their little numbers did not show statistically significance.
They were 592 male patients representing (77.5 %) and 172female patients representing (22.5%). Total ages ranging from 39 to 74 with mean age was 58.31 years old (±8.43SD).
Lung cancer incidence in Urbanrepresented (63.61%) while inRural was (36.39%).
Smoker patients were(72.64%) and the rest of them were non smokers (22.12%) and ex- smokers (5.23%).
COPD is an imporatant risk factor for lung cancer pesented in (58.89%) of the patients.
The main presenting complaint is dyspnea (70.28%), cough presents (69.37%), chest pain (37.17%) and haemopysis (29.18%).
Patients presented with systemic symptoms like weight loss represented (15.05%), fever (14.01%), loss of appetite (11.78%).
Patients presented with pressure symptomswere 8.64%.Dysphgia was (40.91%) and hoarseness of voice was (59.09%) , clubbing were (35.86%),palpable lymph node were (7.98%). Supraclavicular represented (55.74%), and Cervical represented (44.26%).Sputum cytology was positive in (19.76%) of the patients.
PatientswithfreeX-rayrepresented(6.67%). upper zonal(31.94%), midzonal(30.07%) , lowerzonal(13.74%) and hilar(15.57%) and Centralmasswas in 50.65% ofthepatientsand peripheral mass (49.35%).
Total cases who had metastasis at time of diagnosis were (14.53%). Lung and pleura represented (34.23%), bone (31.53%) ,brain (23.42%) , hepatic (10.81%).
Pathological lesions detected with lung cancer were pleural effusion in (26.44%) patients, Collapse (16.10%) andPneumonia (15.71%).
Total cases who did bronchoscope 420 (54.97%) with finidings: mass represented (58.57%), mucosal infiltration was (30.95%), luminal narrowing (7.62%) and external compression (2.86%).
Patients who were diagnosed by bronchoscope represented(49.21%),byC.T guided biopsy (37.96%)and (12.83%) with U.S guided biopsy
Finally we can conclude the following:
1. Males are more common to develop lung cancer than females.
2. Lung cancer incidence in Urban ismore than inRural areas.
3. Smoking is considered as a major risk factor for lung cancer.
4. COPD patients are more likely to develop lung cancer.
5. Dyspnea and chronic cough may be alarming symptoms for lung cancer
6. CT scan of the chest is very important tool forlung cancer staging and before taking biopsy
7. Tissue biopsy and other histopathological diagnostic procedures should be done with satisfactory amount &way.
8. Patients presented with pleural effusion should be investigated thoroughly to rule out possibility of malignancy especially adenocarcinoma type.
All Patients underwent Full history taking with special emphasize on smoking history including smoking state. clinical examination including both general &local examination of the chest, radiological examination including plain chest x-ray posteroanterior view, Computed Tomography of the chest , methods of diagnosis and tools of getting tissue biopsy for confirmatory diagnosis.
There were 800 patients with lung cancer adenocrcinoma was 298 (37.25%), squamous cell carcinoma 196 (24.50%) , small cell carcinoma 171(21.38%), large cell carcinoma 99 (12.38%), 25 metastasis (3.13%) and others 11 (1.38%) including other types of bronchogenic carcinoma and non conclusive ones.
The statistical analysis and differences included 764 subject only excluding (metastasis and other types) because their little numbers did not show statistically significance.
They were 592 male patients representing (77.5 %) and 172female patients representing (22.5%). Total ages ranging from 39 to 74 with mean age was 58.31 years old (±8.43SD).
Lung cancer incidence in Urbanrepresented (63.61%) while inRural was (36.39%).
Smoker patients were(72.64%) and the rest of them were non smokers (22.12%) and ex- smokers (5.23%).
COPD is an imporatant risk factor for lung cancer pesented in (58.89%) of the patients.
The main presenting complaint is dyspnea (70.28%), cough presents (69.37%), chest pain (37.17%) and haemopysis (29.18%).
Patients presented with systemic symptoms like weight loss represented (15.05%), fever (14.01%), loss of appetite (11.78%).
Patients presented with pressure symptomswere 8.64%.Dysphgia was (40.91%) and hoarseness of voice was (59.09%) , clubbing were (35.86%),palpable lymph node were (7.98%). Supraclavicular represented (55.74%), and Cervical represented (44.26%).Sputum cytology was positive in (19.76%) of the patients.
PatientswithfreeX-rayrepresented(6.67%). upper zonal(31.94%), midzonal(30.07%) , lowerzonal(13.74%) and hilar(15.57%) and Centralmasswas in 50.65% ofthepatientsand peripheral mass (49.35%).
Total cases who had metastasis at time of diagnosis were (14.53%). Lung and pleura represented (34.23%), bone (31.53%) ,brain (23.42%) , hepatic (10.81%).
Pathological lesions detected with lung cancer were pleural effusion in (26.44%) patients, Collapse (16.10%) andPneumonia (15.71%).
Total cases who did bronchoscope 420 (54.97%) with finidings: mass represented (58.57%), mucosal infiltration was (30.95%), luminal narrowing (7.62%) and external compression (2.86%).
Patients who were diagnosed by bronchoscope represented(49.21%),byC.T guided biopsy (37.96%)and (12.83%) with U.S guided biopsy
Finally we can conclude the following:
1. Males are more common to develop lung cancer than females.
2. Lung cancer incidence in Urban ismore than inRural areas.
3. Smoking is considered as a major risk factor for lung cancer.
4. COPD patients are more likely to develop lung cancer.
5. Dyspnea and chronic cough may be alarming symptoms for lung cancer
6. CT scan of the chest is very important tool forlung cancer staging and before taking biopsy
7. Tissue biopsy and other histopathological diagnostic procedures should be done with satisfactory amount &way.
8. Patients presented with pleural effusion should be investigated thoroughly to rule out possibility of malignancy especially adenocarcinoma type.
Other data
| Title | STUDY OF CLINICAL AND DIAGNOSTIC DATA IN PATIENTS WITH LUNG CANCER AT ABBASSIA CHEST HOSPITAL FROM JANUARY 2010 TO DECEMBER 2013 | Other Titles | دراسة المعلومات الاكلينيكية والتشخيصية الخاصة بمرضي سرطانالرئة بمستشفي صدر العباسية في الفترةمن يناير 2010 الي ديسمبر2013 | Authors | Basma Malak Zaki | Issue Date | 2014 |
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