EVALUATION OF EARLY MEASUREMENT OF GRANULOCYTE COLONY -STIMULATING FACTOR AND INTERLEUKIN,AND ITS IMPACT ON THE SEVERITY, PROGNOSIS AND OUTCOME OF SYSTEMIC INFLAMMATORY RESPONSE SYNDROME
GALAL HASSAN SHALABY ABDEL NABY;
Abstract
Septic shock was considered among the most common causes of mortality in ICU. Despite the great evolution in the field of
treatment modalities as antibiotics, advanced surgical interventions and critical care, there is an unsatisfactory improvement in the mortality rate. No available effective treatment is present for this chemically and pathologically sofisticated process.
Cytokines play an important role in occurance of SIRS, sepsis and multi-organ failure. A series of pro-inflammatory cytokines such as interleukin 1, 6 and 8 are comndemned in occurance of the inflammatory cascade at the endothelium which may cause early mortality. This may be followed by secreation of another group of anti-inflamatory cytokines such as IL-10 and G-CSF which may help in improvement of cases or occuance of immuno-paralysis which may be the cause of delayed mortality.
treatment modalities as antibiotics, advanced surgical interventions and critical care, there is an unsatisfactory improvement in the mortality rate. No available effective treatment is present for this chemically and pathologically sofisticated process.
Cytokines play an important role in occurance of SIRS, sepsis and multi-organ failure. A series of pro-inflammatory cytokines such as interleukin 1, 6 and 8 are comndemned in occurance of the inflammatory cascade at the endothelium which may cause early mortality. This may be followed by secreation of another group of anti-inflamatory cytokines such as IL-10 and G-CSF which may help in improvement of cases or occuance of immuno-paralysis which may be the cause of delayed mortality.
Other data
| Title | EVALUATION OF EARLY MEASUREMENT OF GRANULOCYTE COLONY -STIMULATING FACTOR AND INTERLEUKIN,AND ITS IMPACT ON THE SEVERITY, PROGNOSIS AND OUTCOME OF SYSTEMIC INFLAMMATORY RESPONSE SYNDROME | Other Titles | تقييم القياس المبكر للعامل الحفاز لانتاج كرات الدم البيضاء المحببة والانترلوكينات 6 و 8 و 10 وتأثيره على شدة الاصابة والتوقع المستقبلى لحالات المتلازمة الاستجابية الالتهابية العامة | Authors | GALAL HASSAN SHALABY ABDEL NABY | Issue Date | 2004 |
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