GINGIVAL CREVICULAR FLUID LEVEL OF BONE MORPHOGENIC PROTEIN - 2 USING MINIMAL INVASIVE APPROACH VERSUS CONVENTIONAL APPROACH IN TREATMENT OF INTRA BONY DEFECT

Abstract

Chronic periodontitis is a challenging disease facing clinicians as it destruct 3 different tissues originating from different cells each is requiring specific treatment modality. Periodontal regeneration involving usage of bone grafts, membranes was offered as one of the best available options for treatment with the application of different surgical approaches that offer enhanced blood clot stability resulting in increased release of growth factors stimulating wound healing and tissue regeneration. The role of BMP-2 in periodontal regeneration is controversial, with different speculations.

This study was done on fifteen patients suffering from chronic periodontitis with it's different classifications in this prospective clinical trial, a split –mouth design of two interproximal contralateral defects were randomly selected (coin toss) and assigned to either group 1 in which modified minimal invasive surgical technique (M-MIST) was performed, PRF and bovine xenograft were used as regenerative materials or group 2 in which conventional surgical approach was performed ,PRF and bovine xenograft were used as regenerative materials.