Some Biophysiological Effects Of “Bromadiolone" On White Rat
AZZA MAHMOUD AWAD;
Abstract
The present investigation aims to determine the possible toxicological eflect of the rodenticide bromadiolone " Super Kaid" on different biochemical and physiological aspects of the white rat Rallus norvegicus treated with three doses ( 1.125. 0.563 and
0.281 mg I kg body weight, stomach intubation). Rats divided into four groups as follows•
group (1 ): untreated animals.
group (2): animals treated with 1.125 mg bromadiolone /kg body weight . stomach intubation.
group (3): animals treated with 0.563 mg bromadiolone/kg body weight stomach
intubation.
group (4): animals treated with 0.281 mg bromadiolonc I kg body weight. stomach intubation.
Blood and tissues samples ( Liver. Brain and muscle) were taken after 24. 48. 72 and 120 hours ofbromadiolone administration and the results showed that
The arterial blood P02 increased significantly after 72 hours in the second group where decreased significantly after 24 & 48 hours and decreased also after 24, 48 and
120 hours in the third group, and increased significantly after 24, 48 and 72 hours while decreased after 120 hours in the fourth group.
- The venous blood P02 decreased in the three treated doses than untreated group except after 72 and 48 hours for the second and fourth group. The decrease in arterial PO, in some experimental periods may be due to the increase of oxygen demands by
the rat tissues and the disturbances in the metabolic rates during these periods.
0.281 mg I kg body weight, stomach intubation). Rats divided into four groups as follows•
group (1 ): untreated animals.
group (2): animals treated with 1.125 mg bromadiolone /kg body weight . stomach intubation.
group (3): animals treated with 0.563 mg bromadiolone/kg body weight stomach
intubation.
group (4): animals treated with 0.281 mg bromadiolonc I kg body weight. stomach intubation.
Blood and tissues samples ( Liver. Brain and muscle) were taken after 24. 48. 72 and 120 hours ofbromadiolone administration and the results showed that
The arterial blood P02 increased significantly after 72 hours in the second group where decreased significantly after 24 & 48 hours and decreased also after 24, 48 and
120 hours in the third group, and increased significantly after 24, 48 and 72 hours while decreased after 120 hours in the fourth group.
- The venous blood P02 decreased in the three treated doses than untreated group except after 72 and 48 hours for the second and fourth group. The decrease in arterial PO, in some experimental periods may be due to the increase of oxygen demands by
the rat tissues and the disturbances in the metabolic rates during these periods.
Other data
| Title | Some Biophysiological Effects Of “Bromadiolone" On White Rat | Other Titles | بعض التأثيرات البيوفسيولوجية " للبروماديلون " على الفأر الأبيض | Authors | AZZA MAHMOUD AWAD | Issue Date | 1998 |
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