BIOCHEMICAL AND TOXICOLOGICAL INFLUENCES OF SOME INSECTICIDES ON BIOTIC ECOSYSTEM

Abstract

The aim of this results is to study the biochemical toxicity of Fenitrothion, cyphenothrin, azadirachtin and pyriproxyfen administered orally at 1/10 LDso aganist the white albino rat. The histopatnological examination for kidney and liver was also considered.

The obtained results indicate the importance of the insecticide type and period after administration in determining the biochemical toxicity on liver and kidney functions.

Data concerning the blood toxicity of tested insecticides on the blood of white albino rats proved the importance of insecticide type, and time after administration in determining the toxic effect on blood parameters.

Histopathological studies on rat organs showed that the liver and kidney damage as a result of insecticide treatri:lent. Azadirachtin 75%, and Pyriproxyfen 10% had relatively caused more pathological changes in the liver after 2 and 6 weeks as congestion, hydropic degeneration, necrosis and lymphocytic infiltration. While Fenitrothion 50% caused hydropic degeneration only and cyphenothrin 5% caused congestion and lymphocytic after 6 weeks.

On the other hand, Azadirachtin 75%, cyphenothrin 5%, and pyriproxyfen 10% proved more potency on the kidney caused tubular degeneration after 2 and 6 weeks, but the four tested insecticides azadirachtin, fenitrothion, cyphenothrin and pyriproxyfen caused in general casts which varying present due to the type of insecticide used after 2 weeks and 6 weeks