Studies on Innovative Systems Based on Nano-Sized Carbohydrate Polymer/Metal Nanoparticles and their Applications in Medical and Other Purposes

Abstract

The candidates own work aims at creation of innovative systems for application in medical domains notably drug delivery and wound healing. Such systems are based on nano-sized carbohydrate polymer. For convenience the work is divided into six chapters dealing with the preparation, characterization and utilization of these systems in medical domains are summarized under. Chapter 1: Ultra-Microstructural features of perborate oxidized starch Oxidation of native maize starch (NS) using Sodium perborate at these different concentrations yields three levels of oxidized starches. The latter include low-, medium-, and highly oxidized starches; nominated as LOS, MOS and HOS respectively. The ultrafine structures of these oxidized starches along with native starch were monitored using world - class facilities. Results obtained bring into focus conclusions given under: (a) The FT-IR and X-ray diffraction patterns indicate the creation of carbonyl groups and a decrease in the crystalinity shape of starch during oxidation; in accordance with the results of carbonyl and carboxyl groups obtained through chemical analysis