FMS Like tyrosine Kinase 3 (FLT3) gene mutations in Acute Myeloid Leukemia (AML) In Patients with Low or Intermediate risk Karyotypes

Essam Hamed Elnoshokaty;

Abstract


Both ITD and D835 mutations of the fms-like tyrosine kinase (FLT3) gene cause constitutive activation of the receptor, in the absence of ligand. We have examined a cohort of 60 newly diagnosed AML patients to determine the prevalence of these mutations an


Other data

Title FMS Like tyrosine Kinase 3 (FLT3) gene mutations in Acute Myeloid Leukemia (AML) In Patients with Low or Intermediate risk Karyotypes
Other Titles الطفرات الوراثية فى جين إف إم إس شبيه التيروزين كيناز 3(إف إل ت 3 )فى سرطان الدم الميلودى الحاد فى المرضى ذوى التركيب الكروموزومى الجيد أو المتوسط الخطورة
Authors Essam Hamed Elnoshokaty
Keywords FMS Like tyrosine Kinase 3 (FLT3) gene mutations in Acute Myeloid Leukemia (AML) In Patients with Low or Intermediate risk Karyotypes
Issue Date 2009
Description 
Both ITD and D835 mutations of the fms-like tyrosine kinase (FLT3) gene cause constitutive activation of the receptor, in the absence of ligand. We have examined a cohort of 60 newly diagnosed AML patients to determine the prevalence of these mutations an

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