Adjuvant Therapy in Benign Bone Lesions

Abstract

Benign bone tumors represent a heterogenous group of bone lesions with variable histopathological characteristics and biological behavior, which can result in important alterations in the bone architecture, causing not only mechanical fragility but also destruction of the adjacent joints. The term “tumor-like lesions of bone” summarizes various conditions of non-neoplastic nature originating from or affecting the bone and presenting as solitary or sometimes multiple bone lesions. The most important lesions of this group are even congenital, inflammatory, ischemic, and traumatic disorders, can appear in this fashion and therefore could be added to this selection. Different fibro-osseous and cystic lesions represent the most common entities in this group with nonossifying fibroma, simple and aneurysmal bone cyst being the most frequent. The diagnosis of bone tumors represents a “team diagnosis” elaborated by and necessitating close cooperation of orthopedic surgeons, radiologists, and pathologists, the radiologist’s contribution is the most responsible and most important in cases of benign bone lesions. The primary aim of imaging should be a specific diagnosis (in the ideal case obviating the need for biopsy) or narrowing of the differential diagnosis, in order to decide whether biopsy, surgical intervention, or simple observations are required for further management. The treatment of benign lesions range from just observation as a conservative treatment to surgical treatment in the form of intralesional surgery depending on the stage of the tumor. The treatmemt should should be individualized, aiming to reduce recurrence and to preserve function.