CLINICAL CORRELATIONS WITH THE LEVEL OF THE COMPLEMENT ONE (Q) IN SERUM OF RHEUMATOID ARTHRITIS PATIENTS

Abstract

In inflammatory joint disorders like RA, it is vital to be able to assess the activity, progression and therapeutic response of the patient, In the present study, 30 rheumatoid arthritis patients, attending the Rheumatology and Rehabililation out patient clinic of Cairo University hospitals were each assessed for the following: Articular index duration of morning stiffness, Clq serum level, RF, ESR, CD4 : CDS a correlation was done between different clinical and laboratory indices of disease activity and we found that:-

• There was a significant correlation between the articular index and duration of disease and no significant correlation between Articular index and other clinical or laboratory indices.

• There was no significant correlation between serum level of Clq and any of other clinical indices of the disease. Also no significant correlation between serum level of Clq and ESR, CD4, CDS, ratio of CD4 to CDS but there was significant correlation between Clq serum level and RF.

• There was no significant correlation between CDS cell percentage. and RF, duration of disease, morning stiffness, articular index and Clq. But there was a significant negative correlation between the (CDS) cells percentage and ESR.

• There was a high significant correlation between ESR and the ratio between CD4 and CDS cells. Also there was a high significant relation between the percentage of CD4 cells and ESR.