Expression and immune recognition of polypeptides derived from Hepatitis C virus structural proteins

Halim, Alyaa S Abdel; Mohamed, Mohamed R; Abdel Hamid, Fatma; Karim, Amr M;

Abstract


Hepatitis C virus (HCV) is characterized by a high degree of nucleotide sequence variability between genotypes. This variability extends to functional and immunological determinants. Serological tests using antigenic segments derived from the HCV polyprotein have been used for the diagnosis of HCV infection. However, available diagnostic Kits do not necessarily take type variability into consideration and are not optimized for HCV genotype 4a (HCV4a), the predominant genotype in Egypt.


Other data

Title Expression and immune recognition of polypeptides derived from Hepatitis C virus structural proteins
Authors Halim, Alyaa S Abdel ; Mohamed, Mohamed R ; Abdel Hamid, Fatma ; Karim, Amr M 
Issue Date Jan-2019
Journal Indian journal of pathology & microbiology 
DOI 43-48
0974-5130
1
48
https://api.elsevier.com/content/abstract/scopus_id/85060947171
62
10.4103/IJPM.IJPM_604_18
PubMed ID 30706858
Scopus ID 2-s2.0-85060947171

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