(Comparison Between the Effects of Stem Cells and Lepidium Sativum on the Healing of Extraction Socket in Albino Rats (Histological and Immunohistochemical Study

Abstract

Knowledge about the healing process at extraction sites, including contour changes caused by bone resorption and remodeling, is essential (Lam, 1960; Schropp, 2003). Several strategies have been reported to accelerate bone healing (Giannoudis et al., 2005; Basmanav et al., 2008; Dimitriou et al., 2011). The objective of this study was to evaluate and compare between the effects of stem cells and Lepidium sativum on the healing of extraction socket in albino rats and if they could promote new bone formation in the alveolar socket following tooth extraction. Materials and methods: Forty-five adult male albino rats weighing 180-200 grams were used in this study. The first mandibular molars were a-traumatically extracted under sterile conditions, and general anesthesia. The rats classified into 3 groups each of them was consisted of 15 animals.