A Study of Serum Interleukin-33 among Patients with Pediatric Atopic Diseases
Hossam Mohammed Ibrahim Shahda;
Abstract
he pediatric atopic diseases consist of asthma, allergic rhinitis, atopic dermatitis and angioedema.
Interleukin (IL)-33, a cytokine, produced when epithelial and endothelial cells are exposed to stimuli. The IL-33- induced production of pro-inflammatory cytokines is a critical event that aggravates atopic diseases such as asthma, atopic dermatitis, and pollenosis.
The aim of the current study was to evaluate measurement of the serum level of Interleukin-33 (IL-33) in pediatric patient of allergic diseases like bronchial asthma, allergic rhinitis, atopic dermatitis and angioedema for detection of prognostic gain from adding this marker to the work up of these diseases indicating the disease severity and potential therapeutic targets.
This study was case control study included 140 children divided into 2 groups, the study group which included 70 children subdivided into bronchial asthma, allergic rhinitis, angioedema and atopic dermatitis and the control group which included 70 healthy children from the outpatient clinic in Ain Shams University Children’s Hospital after exclusion of personal or family history of atopic diseases or chronic diseases.
Interleukin (IL)-33, a cytokine, produced when epithelial and endothelial cells are exposed to stimuli. The IL-33- induced production of pro-inflammatory cytokines is a critical event that aggravates atopic diseases such as asthma, atopic dermatitis, and pollenosis.
The aim of the current study was to evaluate measurement of the serum level of Interleukin-33 (IL-33) in pediatric patient of allergic diseases like bronchial asthma, allergic rhinitis, atopic dermatitis and angioedema for detection of prognostic gain from adding this marker to the work up of these diseases indicating the disease severity and potential therapeutic targets.
This study was case control study included 140 children divided into 2 groups, the study group which included 70 children subdivided into bronchial asthma, allergic rhinitis, angioedema and atopic dermatitis and the control group which included 70 healthy children from the outpatient clinic in Ain Shams University Children’s Hospital after exclusion of personal or family history of atopic diseases or chronic diseases.
Other data
| Title | A Study of Serum Interleukin-33 among Patients with Pediatric Atopic Diseases | Authors | Hossam Mohammed Ibrahim Shahda | Issue Date | 2018 |
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