RECENT TRENDS IN MANAGEMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM COMPLICATIONS AFTER OPEN CARDIAC SURGERY
Hadal Hassan Mohsen;
Abstract
The- Gentral nervous• system comprises the brain and spinal cord. The blood sapplvi:ig tl]e brain is about 15 percent
of the cardiac output.
"
-- ...... •- ,. •-
Regulation of cerebral blood flow is by either cerebral perfusion pressure, result in (:erebral vasodilatation while elevation induces vasoconstriction, and extrinsic mechanisms which include effect of PaC0 2, Pa02, temperature viscosity and autonomic influences.
During open-heart surgery, the interruption of cardiopulmonary blood flow depends upon three essential functions performed by the cardiopulmonary bypass apparatus, which are, oxygenation of venous blood, elimination of carbon dioxide and maintenance of systolic perfusion.
Pathophysiology of cerebral dysfunction after open-heart operation depends on the fact that the brain has a high rate of energy utilization and a very limited energy storage capacity. It is there for extremely vulnerable in the event of interruption of substrate (oxygen, glucoses supply).
Causes of cerebral dysfunction are cerebral macro- and micro- emboli or period of hypoperfusion.
Risk factors of neurological injury after cardiac surgery include old age, poor preoperative cardiac functions ascending aortic at_IJ_erosclerosis, diabetes mellitus and genetic
susceptibility.
of the cardiac output.
"
-- ...... •- ,. •-
Regulation of cerebral blood flow is by either cerebral perfusion pressure, result in (:erebral vasodilatation while elevation induces vasoconstriction, and extrinsic mechanisms which include effect of PaC0 2, Pa02, temperature viscosity and autonomic influences.
During open-heart surgery, the interruption of cardiopulmonary blood flow depends upon three essential functions performed by the cardiopulmonary bypass apparatus, which are, oxygenation of venous blood, elimination of carbon dioxide and maintenance of systolic perfusion.
Pathophysiology of cerebral dysfunction after open-heart operation depends on the fact that the brain has a high rate of energy utilization and a very limited energy storage capacity. It is there for extremely vulnerable in the event of interruption of substrate (oxygen, glucoses supply).
Causes of cerebral dysfunction are cerebral macro- and micro- emboli or period of hypoperfusion.
Risk factors of neurological injury after cardiac surgery include old age, poor preoperative cardiac functions ascending aortic at_IJ_erosclerosis, diabetes mellitus and genetic
susceptibility.
Other data
| Title | RECENT TRENDS IN MANAGEMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM COMPLICATIONS AFTER OPEN CARDIAC SURGERY | Other Titles | الاتجاهات الحديثه فى علاج ومنع المضاعفات التى تصيب الجهاز العصبى المركزى بعد جراحات القلب المفتوح | Authors | Hadal Hassan Mohsen | Issue Date | 2002 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.