Neuron-specific Enolase, Serum100 B, Electroencephalography as Indicators of Extent of Brain Damage in Post Cardiac Arrest Patients

Abstract

ardiac arrest is one of the greatest medical emergencies with fatal outcome unless quickly corrected by resuscitation techniques. Advancement in resuscitation techniques has resulted in development of new disease entity termed 'Post cardiac arrest syndrome' which is a unique and complex combination of pathophysiological processes resulting from Cardiac arrest. Prediction of outcome in post cardiac arrest patients is a major ethical, medical, and economic challenge. A false prediction of poor outcome can lead to early withdrawal of care. A false optimistic prediction may lead to unnecessary prolongation of costly therapy. Multimodal strategy is needed in prediction of outcome in post cardiac arrest patients including Clinical neurological examination, Neurophysiology, Brain imaging, Biomarkers and Electroencephalogram. Certain EEG patterns have the potential to predict poor outcome after cardiac arrest. The aim of our study was to study Neuron-specific enolase, Serum B100, Electroencephalogarm in post cardiac arrest pediatric patients and correlate them with cardiac arrest circumstances and patients' outcome.