Comparative Study Between The Efficacy Of Lornoxicam Vs Fentanyl In Attenuating The Hemodynamic Response To Laryngoscopy And Endotracheal Intubation

Abstract

During general anesthesia, airway control is generally provided by endotracheal intubation. Laryngoscopy prior to intubation and intubation in itself produce a significant hemodynamic stress in the form of tachycardia and hypertension, these hemodynamic changes are usually transient, variable, and unpredictable. These changes may be of no consequence in healthy individuals, but they may be hazardous in patients with hypertension, myocardial ischemia, cerebrovascular diseases, and those with increased intraocular pressures. Various drugs and techniques have been used from time to time for attenuating the stress response including opioids lidocaine beta blockers calcium channel blockers vasodilators and α2 agonists. However, no modality was devoid of drawbacks and limitations and the hunt for ideal drug continues.