SYNTHESIS AND STUDIES OF SOME CONDENSED PYRIDONE DERIVATIVES

Abstract

This work has been carried out to investigate the utility of 1,6- diamino-3,5-dicyano-4-methylpyridin-2-one for the synthesis of a variety of new heterocyclic systems such as 1,6-diamino-3,5-dicyano-4- (arylhydrazonomethine)pyridin-2-one, 2,3-di-amino-1,2,11,12- tetrahydro-1,12-dioxo-pyrido(3',4': 5',4']pyridazino[3,2-b]quinazoline-4- carbonitrile, 2,3,8-triamino-6-aryl-7-thioamideiso-quinolin-1-one, 2,3,8-triamino-4,7-dicyano-6-arylisoquinolin-1-one, 2,3,8-triamino-4- cyano-7-ethoxycarbonyl-6-arylisoquinolin-1-one, 2,3-diamino-4,7.7- tricyano-5,6.7-trihydro-8-imino-6-methyl-6-phenylisoquinolin-1-one, 2,3-diamino-4,6,7,7-tetracyano-8-iminoisoquinolin-1-one, 2,3,8- triamino-4-cyano-6-thiocarbonyl-7-arylpyrido[3,4-c]pyridin-2-one, 1,5- diamino-7-cyano-8-methylpyrido[2,3-d]pyrimidin-6-one, 5-amino-7- cyano-1-hydroxy-8-methylpyrido[2,3-d]pyrimidin-6-one, 4,6-dicyano- 1,2,3-trihydro-5-methyl-2, 7-dioxotriazolo[2,3-a]pyridine, 4,6-dicyano-5- methyl-7-oxotriazolo[2,3-a]pyridine, 4,6,7-triamino-1,2,3.4,5,6- hexahydro-1,3,5-trioxo-2-phen-ylpyrrolo[3,4-e]isoquinoline-8-carbo­ nitrile, 2-amino-4,6-dicyano-5-methyl-7-oxotriazolo[2,3-a]-pyridine, 2,3,7-triamino-4-cyano-1-oxothieno[3,4-c]pyridine derivatives of potential biological activity.