Screening of Autism Spectrum Disorder in Metabolic Disorders by Modified Checklist of Autism-Revised/Follow-up

Abstract

The global prevalence of ASD has markedly increased in the recent years. Autism and Developmental Disabilities Monitoring (ADDM) Network from the Centers for Disease Control and Prevention identified that 1 in 59 or 1.7% of 8-year-olds was diagnosed as ASD. In Egypt, the median rate is 62 cases per 10,000 individuals with average rate 4.3: 1 male to female ratio. Also an Egyptian screening study for ASD flagged a considerable result which was (23.8%) of Egyptian toddlers were suspected to have ASD. ASD etiology is still a confusing question without a definite answer. It has long been presumed that there is a common cause at the genetic, cognitive, and neural levels for autism's characteristic symptoms. During last decades