Efficacy of Dexmedetomidine as an Adjuvant to Bupivacaine in Peripheral Nerve Block - Three Prospective Randomized Controlled Studies

Abstract

Brachial plexus is a complex network of nerves supplying the whole upper limb, including it’s motor and sensory supply. Arising from the neck, passing through the axilla to the upper limb. It is composed of 5 roots, 3 trunks, 6 divisions, 3 cords, and terminal branches. Supraclavicular brachial plexus block is frequently used for upper limb surgeries The paravertebral space contains dorsal and ventral rami and the sympathetic chain. Thoracic Paravertebral nerve block is used for breast surgeries either a single modality or as adjuvant to general anesthesia. It involves injection of local anesthetic at the site where the spinal nerve emerges from the intervertebral foramina. Hence. results in unilateral sensory, motor and sympathetic blockade.