Role of fecal B-cell activating factor (BAFF) as a new non-invasive marker in evaluation of Ulcerative colitis patients
Bishoy Samir Ibrahim Abdel Malek;
Abstract
ABSTRACT
Background: Ulcerative colitis is a chronic inflammatory disease of the colon, that is characterised by attacks of remission and exacerbations, The diagnosis is suspected clinically and confirmed through endoscopic biopsy, it needs to be followed up and assessed by non-invasive biomarkers, one of these biomarkers is fecal calprotectin. Recently B cell-activating factor (BAFF), a new biomarker, has been proposed to be a regulator of B cell and T cell immune responses and be associated with inflammatory processes in autoimmunity and B cell malignancies.
Aim: To investigate the role of faecal BAFF in monitoring activity of Ulcerative Colitis.
Background: Ulcerative colitis is a chronic inflammatory disease of the colon, that is characterised by attacks of remission and exacerbations, The diagnosis is suspected clinically and confirmed through endoscopic biopsy, it needs to be followed up and assessed by non-invasive biomarkers, one of these biomarkers is fecal calprotectin. Recently B cell-activating factor (BAFF), a new biomarker, has been proposed to be a regulator of B cell and T cell immune responses and be associated with inflammatory processes in autoimmunity and B cell malignancies.
Aim: To investigate the role of faecal BAFF in monitoring activity of Ulcerative Colitis.
Other data
| Title | Role of fecal B-cell activating factor (BAFF) as a new non-invasive marker in evaluation of Ulcerative colitis patients | Other Titles | دور العامل المنشط للخلايا المناعية ب في البراز كعامل غير تدخلي في تقييم مرضى القولون التقرحي | Authors | Bishoy Samir Ibrahim Abdel Malek | Issue Date | 2019 |
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