Assessment of Serum Interleukin-19 in Acne Vulgaris Patients of Different Clinical Severities

Abstract

cne vulgaris is a multifactorial inflammatory skin disease of the pilosebaceous follicle, caused by host, environmental factors, and microbial components. The pathogenesis of acne is thought to involve an interplay between a number of factors, including excess androgenic stimulation, sebum hyper secretion, abnormal differentiation, proliferation and hyper keratinization of the epidermal keratinocytes, especially those lining the duct region of the sebaceous unit. Typical features of acne include microcomedones, comedones, papules, nodules (large papules), pustules, and often results in scarring (Das & Reynolds, 2014). The severity of acne can be classified as mild, moderate, or severe as this helps to determine an appropriate treatment regimen (Lehmann et al., 2002). Many treatment options for acne are available, including lifestyle changes, medications, medical procedures, and laser treatments (Neil and Andrea, 2018).