Silymarin and silymarin nanoparticles guard against chronic unpredictable mild stress induced depressive-like behavior in mice: involvement of neurogenesis and NLRP3 inflammasome
Ashraf, Aya; Mahmoud, Passant A; Reda, Haidy; Mansour, Salma; Helal, Mehad H; Effat, Haidy; Nasr, Maha;
Abstract
The neuropathology of depression is quite complex. Thus, treatment failures are frequent with current antidepressants, raising the need for more effective ones.
Other data
| Title | Silymarin and silymarin nanoparticles guard against chronic unpredictable mild stress induced depressive-like behavior in mice: involvement of neurogenesis and NLRP3 inflammasome | Authors | Ashraf, Aya; Mahmoud, Passant A; Reda, Haidy; Mansour, Salma; Helal, Mehad H; Effat, Haidy ; Nasr, Maha | Keywords | Chronic unpredictable mild stress;NLRP3;brain-derived neurotrophic factor;nanoparticles;silymarin | Issue Date | 2019 | Journal | Journal of psychopharmacology | Volume | 33 | Issue | 5 | Start page | 615 | End page | 631 | ISSN | 0269-8811 1461-7285 |
DOI | 10.1177/0269881119836221 | PubMed ID | 30896354 |
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