Assessing the impact of a combination of sofosbuvir and daclatasvir treatment for hepatitis C virus infection on heart rate, rhythm and heart rate variability using 24-hour ECG monitoring

El Missiri, Ahmed; Rayan, Mona Mostafa; Awad, Mohamed Medhat; El Desoky, Ahmed Ibrahim;

Abstract


Direct-acting antiviral agents (DAAs) cure patients with hepatitis C virus (HCV) infection. Concerns have arisen the occurrence of significant bradyarrhythmias during treatment with DAAs. The aim of this study was to assess the impact of a DAA combination for the treatment of HCV infection on heart rate, rhythm, and heart rate variability (HRV) using 24-h ECG monitoring.


Other data

Title Assessing the impact of a combination of sofosbuvir and daclatasvir treatment for hepatitis C virus infection on heart rate, rhythm and heart rate variability using 24-hour ECG monitoring
Authors El Missiri, Ahmed ; Rayan, Mona Mostafa; Awad, Mohamed Medhat; El Desoky, Ahmed Ibrahim
Keywords Bradycardia;Sofosbuvir;Holter;ECG monitoring;Daclatasvir
Issue Date 1-Jul-2020
Journal The Egyptian Heart Journal 
Volume 72
Issue 37
ISSN 2090-911X
DOI 10.1186/s43044-020-00070-4
PubMed ID 32613565

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