Novel hydrazinocurcumin derivative loaded chitosan, ZnO, and Au nanoparticles formulations for drug release and cell cytotoxicity

Hassan, Hemat; Abir S. Nasr; Kandile, Nadia;

Abstract


Synthesis of new hydrazinocurcumin derivative 4-((E)-2-(1-(4-Methoxy benzyl)-6-p-tolylpyridazin-3-yl)-3-
((E)-4-hydroxy-3-methoxystyryl)-1H-pyrazol-5-yl)vinyl)-2-methoxyphenol (HCUR) through the reaction of
curcumin (CUR) with 1- (4-(2-Methoxybenzyl)-6-p-tolylpyridazin-3-yl)hydrazine(VII).


Other data

Title Novel hydrazinocurcumin derivative loaded chitosan, ZnO, and Au nanoparticles formulations for drug release and cell cytotoxicity
Authors Hassan, Hemat ; Abir S. Nasr; Kandile, Nadia 
Keywords Hydrazinocurcumin derivative;Chitosan, Nanoparticles;Drug release;Cell cytotoxicity
Issue Date 7-May-2020
Publisher Elsevier
Journal International Journal of Biological Macromolecules 
Volume 158
Start page 1216
End page 1226
DOI https://doi.org/10.1016/j.ijbiomac.2020.05.015

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