A Split Scalp Study of Single versus Double Spin Platelet-rich plasma Injections in Treatment of Female Pattern Hair Loss: Clinical Effect and Relation to Vascular Endothelial Growth Factor in PRP

Abstract

emale pattern hair loss (FPHL) is the most common hair loss disorder in women. The importance of this disease comes from the intense emotional distress and disrupted self-image caused by the hair loss where there is progressive nonscarring replacement of terminal hair follicles over the frontal and vertex regions by miniaturized follicles, which leads progressively to a visible reduction in hair density. Treatment of FPHL remains a challenge as no treatment is either completely curative or preventive. Platelet-rich plasma (PRP) provides an option for patients recalcitrant to the currently approved therapies; minoxidil and finasteride. Moreover, with the annoying daily applications required for the proper use of minoxidil and the growing concern over p